Clinical and psychological aspects in a group of allergic asthma patients and the impact on their health status perception

Authors

Keywords:

allergic asthma, personality, anxiety, depression, HRQoL

Abstract

Background

The interplay between physical and psychological symptoms frequently affects the health-related quality of life of asthma patients.

Participants and procedure

This research aimed at assessing the psychological status of 60 patients attending their first/second doctor visit at which they were diagnosed with allergic asthma. Information on psychological distress was collected through the Symptom Questionnaire (SQ), personality traits were described through Cattell’s 16-Personality Factor Questionnaire (16-PF), stress-related behavior was detected through the P Stress Questionnaire (PSQ), and the perceived quality of life was described with the Rhinasthma questionnaire.

Results

The SQ revealed anxiety levels above the clinical cut-off in 71.7% of patients, levels of depression in 46.7%, angerhostility in 53.3%, and somatic symptoms in 65%. No significant differences were observed after three months. The 16-PF scores were also suggestive of specific personality traits associated with the predisposition towards psychosomatic disorders. However, no stress-related behaviors were observed with the PSQ. Rhinasthma highlighted a certain degree of the perceived quality of life. Additionally, the quality of life correlated with age, all psychological distress scales, a few personality traits, vigor, and stress disorders.

Conclusions

Allergic asthma patients present a  higher-than-average level of psychological distress and impaired perceived quality of life at the time of diagnosis. Therefore, it is important to assess the psychological status in addition to the respiratory function.

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References

Baiardini, I., Pasquali, M., Giardini, A., Specchia, C., Passalacqua, G., Venturi, S., Braido, F., Bonini, S., Majani, G., Canonica, G. W. (2003). Rhinasthma: a new specific QoL questionnaire for patients with rhinitis and asthma. Allergy, 58, 289–294. https://doi.org/10.1034/j.1398-9995.2003.00079.x.

Baiardini, I., Sicuro, F., Balbi, F., Canonica, G. W., & Braido, F. (2015). Psychological aspects in asthma: Do psychological factors affect asthma management? Asthma Research and Practice, 1, 7. https://doi.org/10.1186/s40733-015-0007-1.

Benasi, G., Fava, G. A., & Rafanelli, C. (2020). Kellner’s Symptom Questionnaire, a highly sensitive patient-reported outcome measure: Systematic review of clinimetric properties. Psychotherapy and Psychosomatics, 89, 74–89. https://doi.org/10.1159/000506110.

Bonaguidi, F., Michelassi, C., Trivella, M. G., Carpeggiani, C., Pruneti, C. A., Cesana, G., & L’Abbate, A. (1996). Cattell’s 16 PF and PSY inventory: Relationship between personality traits and behavioral responses in patients with acute myocardial infarction. Psychological Reports, 78, 691–702. https://doi.org/10.2466/pr0.1996.78.2.691.

Bousquet, J., & Kaltaev, N. (2007). Global surveillance, prevention and control of chronic respiratory diseases: a comprehensive approach. Retrieved from https://apps.who.int/iris/handle/10665/43776.

Braido, F., Brusselle, G., Guastalla, D., Ingrassia, E., Nicolini, G., Price, D., Roche, N., Soriano, J. B., & Worth, H. (2016). Determinants and impact of suboptimal asthma control in Europe: The international cross-sectional and longitudinal assessment on asthma control (LIAISON) study. Respiratory Research, 17, 51. https://doi.org/10.1186/s12931-016-0374-z.

Carli, G., Farsi, A., Bormioli, S., Ridolo, E., Fassio, F., Pucci, S., Montevecchi, M., Riparbelli, M., Cosmi, L., Parronchi, P., & Rossi, O. (2021). Management of patients with severe asthma: Results from a survey among allergists and clinical immunologists of the Central Italy Inter-Regional Section of SIAAIC. Clinical and Molecular Allergy, 19, 22. https://doi.org/10.1186/s12948-021-00160-x.

Cattell, R. B. (1956). A shortened “basic English” version (Form C) of the 16 PF Questionnaire. The Journal of Social Psychology, 44, 257–278. https://doi.org/10.1080/00224545.1956.9921928.

Cazzoletti, L., Marcon, A., Janson, C., Corsico, A., Jarvis, D., Pin, I., Accordini, S., Almar, E., Bugiani, M., Carolei, A., Cerveri, I., Duran-Tauleria, E., Gislason, D., Gulsvik, A., Jõgi, R., Marinoni, A., Martínez-Moratalla, J., Vermeire, P., de Marco, R., & Therapy and Health Economics Group of the European Community Respiratory Health Survey (2007). Asthma control in Europe: a realworld evaluation based on an international population-based study. The Journal of Allergy and Clinical Immunology, 120, 1360–1367. https://doi. org/10.1016/j.jaci.2007.09.019.

Ciarrochi, J., Fisher, D., & Lane, L. (2011). The link between value motives, value success, and well-being among people diagnosed with cancer. Psychooncology, 20, 1184–1192. https://doi.org/10.1002/pon.1832.

Cohen, C. (1982). On the quality of life: Some philosophical reflections. Circulation, 66, 29–33.

Colivicchi, F., Abrignani, M. G., & Santini, M. (2010). Aderenza terapeutica: il fattore di rischio occulto [Therapeutic non-adherence: the hidden risk factor]. Giornale Italiano di Cardiologia, 11, 124S–127S.

Corrao, G., Arfè, A., Nicotra, F., Ghirardi, A., Vaghi, A., De Marco, R., Pesci, A., Merlino, L., Zambon, A., & CRD Real-World Evidence Scientific Board (2016). Persistence with inhaled corticosteroids reduces the risk of exacerbation among adults with asthma: a real-world investigation. Respirology, 21, 1034–1040. https://doi.org/10.1111/resp.12791.

Cosentino, C., Sgromo, D., Merisio, C., Berretta, R., & Pruneti, C. (2018). Psychophysiological adjustment to ovarian cancer: Preliminary study on Italian women condition. Applied Psychophysiology and Biofeedback, 43, 161–168. https://doi. org/10.1007/s10484-018-9395-3.

Cottini, M., Licini, A., Lombardi, C., Bagnasco, D., Comberiati, P., & Berti, A. (2021). Small airway dysfunction and poor asthma control: a dangerous liaison. Clinical and Molecular Allergy, 19, 7. https://doi.org/10.1186/s12948-021-00147-8.

Croisant S. (2014). Epidemiology of asthma: Prevalence and burden of disease. In A. Brasier (Ed.), Heterogeneity in asthma (pp. 17–29). Humana Press. https://doi.org/10.1007/978-1-4614-8603-9_2.

De Girolamo, G., De Leo, D., & Galassi, L. (1995). Il progetto OMS sulla valutazione della qualità della vita [The WHO project on quality of life assessment]. In G. A. Fava, F. Pesarin, & N. Sonino (Eds.), Clinimetria (pp. 25–35). Patron.

de Marco, R., Bugiani, M., Cazzoletti, L., Carosso, A., Accordini, S., Buriani, O., Carrozzi, L., Dallari, R., Giammanco, G., Ginesu, F., Marinoni, A., Lo Cascio, V., Poli, A., Struzzo, P., Janson, C., & ISAYA study group (2003). The control of asthma in Italy: a multicentre descriptive study on young adults with doctor diagnosed current asthma. Allergy, 58, 221–228. https://doi.org/10.1034/j.1398- 9995.2003.00059.x.

De Vincenzo, F., Cosentino, C., Quinto, R. M., Di Leo, S., Contardi, A., Guidotti, S., Iani, L., & Pruneti, C. (2022). Psychological adjustment and heart rate variability in ovarian cancer survivors. Mediterranean Journal of Clinical Psychology, 10, 1–18. https://doi.org/10.13129/2282-1619/mjcp-3318.

Dudeney, J., Sharpe, L., Jaffe, A., Jones, E. B., & Hunt, C. (2017). Anxiety in youth with asthma: a meta-analysis. Pediatric Pulmonology, 52, 1121–1129. https://doi.org/10.1002/ppul.23689.

Ebstrup, J. F., Eplov, L. F., Pisinger, C., & Jørgensen, T. (2011). Association between the Five Factor personality traits and perceived stress: Is the effect mediated by general self-efficacy? Anxiety, Stress, and Coping, 24, 407–419. https://doi.org/10.1080/10615806.2010.540012.

Fava, G. A., Kellner, R., Perini, G. I., Fava, M., Michelacci, L., Munari, F., Evangelisti, L. P., Grandi, S., Bernardi, M., & Mastrogiacomo, I. (1983). Italian validation of the Symptom Rating Test (SRT) and Symptom Questionnaire (SQ). Canadian Journal of Psychiatry, 28, 117–123. https://doi. org/10.1177/070674378302800208.

Foster, J. M., McDonald, V. M., Guo, M., & Reddel, H. K. (2017). “I have lost in every facet of my life”: The hidden burden of severe asthma. The European Respiratory Journal, 50, 1700765. https://doi. org/10.1183/13993003.00765-2017.

Gibson, P. G., Powell, H., Coughlan, J., Wilson, A. J., Abramson, M., Haywood, P., Bauman, A., Hensley, M. J., & Walters, E. H. (2003). Self-management education and regular practitioner review for adults with asthma. The Cochrane Database of Systematic Reviews, CD001117. https://doi.org/ 10.1002/14651858.CD001117.

Gillisen, A. (2007). Patient’s adherence in asthma. Journal of Physiology and Pharmacology, 58, 205–222.

Guidotti, S., Coscioni, G., & Pruneti, C. (2022). Impact of COVID-19 on mental health and the role of personality: Preliminary data from a sample of Italian university students. Mediterranean Journal of Clinical Psychology, 10, 1–33. https://doi.org/10.13129/2282-1619/mjcp-3549.

Hashimoto, M., Sato, E. F., Hiramoto, K., Kasahara, E., & Inoue, M. (2010). Role of the hypothalamo-pituitary-adrenal axis in the modulation of pollinosis induced by pollen antigens. Allergology International, 59, 201–206. https://doi.org/10.2332/ allergolint.09-OA-0133.

Höglund, C. O., Axén, J., Kemi, C., Jernelöv, S., Grunewald, J., Müller-Suur, C., Smith, Y., Grönneberg, R., Eklund, A., Stierna, P., & Lekander, M. (2006). Changes in immune regulation in response to examination stress in atopic and healthy individuals. Clinical and Experimental Allergy, 36, 982–992. https://doi.org/10.1111/j.1365-2222.2006.02529.x.

Holmes, J., & Heaney, L. G. (2021). Measuring adherence to therapy in airways disease. Breathe, 17, 210037. https://doi.org/10.1183/20734735.0037- 2021.

Juniper, E. F., Guyatt, G. H., Epstein, R. S., Ferrie, P. J., Jaeschke, R., & Hiller, T. K. (1992). Evaluation of impairment of health-related quality of life in asthma: Development of a questionnaire for use in clinical trials. Thorax, 47, 76–83. https://doi.org/10.1136/thx.47.2.76.

Kallaur, A. P., Lopes, J., Oliveira, S. R., Simão, A. N., Reiche, E. M., de Almeida, E. R., Morimoto, H. K., de Pereira, W. L., Alfieri, D. F., Borelli, S. D., Kaimen-Maciel, D. R., & Maes, M. (2016). Immuneinflammatory and oxidative and nitrosative stress biomarkers of depression symptoms in subjects with multiple sclerosis: Increased peripheral inflammation but less acute neuroinflammation. Molecular Neurobiology, 53, 5191–5202. https://doi.org/10.1007/s12035-015-9443-4.

Lehrer, P., Feldman, J., Giardino, N., Song, H. S., & Schmaling, K. (2002). Psychological aspects of asthma. Journal of Consulting and Clinical Psychology, 70, 691–711. https://doi.org/10.1037//0022-006x.70.3.691.

Mäkelä, M. J., Backer, V., Hedegaard, M., & Larsson, K. (2013). Adherence to inhaled therapies, health outcomes and costs in patients with asthma and COPD. Respiratory Medicine, 107, 1481–1490. https://doi.org/10.1016/j.rmed.2013.04.005.

Megari, K. (2013). Quality of life in chronic disease patients. Health Psychology Research, 1, e27. https:// doi.org/10.4081/hpr.2013.e27.

Miličić, D., Brajković, L., Maček, J. L., Andrić, A., Ardalić, Ž., Buratović, T., & Marčinko, D. (2016). Type a personality, stress, anxiety and health locus of control in patients with acute myocardial infarction. Psychiatria Danubina, 28, 409–414.

Miyasaka, T., Dobashi-Okuyama, K., Takahashi, T., Takayanagi, M., & Ohno, I. (2018). The interplay between neuroendocrine activity and psychological stress-induced exacerbation of allergic asthma. Allergology International, 67, 32–42. https://doi. org/10.1016/j.alit.2017.04.013.

Montoro, J., Mullol, J., Jáuregui, I., Dávila, I., Ferrer, M., Bartra, J., del Cuvillo, A., Sastre, J., & Valero, A. (2009). Stress and allergy. Journal of Investigational Allergology and Clinical Immunology, 19, 40–47.

Morris, G., Reiche, E. M. V., Murru, A., Carvalho, A. F., Maes, M., Berk, M., & Puri, B. K. (2018). Multiple immune-inflammatory and oxidative and nitrosative stress pathways explain the frequent presence of depression in multiple sclerosis. Molecular Neurobiology, 55, 6282–6306. https://doi.org/10.1007/ s12035-017-0843-5.

Nunes, C., Pereira, A. M., & Morais-Almeida, M. (2017). Asthma costs and social impact. Asthma Research and Practice, 3, 1. https://doi.org/10.1186/ s40733-016-0029-3.

Partridge, M. R., van der Molen, T., Myrseth, S. E., & Busse, W. W. (2006). Attitudes and actions of asthma patients on regular maintenance therapy: The INSPIRE study. BMC Pulmonary Medicine, 6, 13. https://doi.org/10.1186/1471-2466-6-13.

Peters, S. P., Jones, C. A., Haselkorn, T., Mink, D. R., Valacer, D. J., & Weiss, S. T. (2007). Real-world evaluation of asthma control and treatment (REACT): Findings from a national Web-based survey. Journal of Allergy and Clinical Immunology, 119, 1454–1461. https://doi.org/10.1016/j.jaci.2007.03.022.

Pinnock, H., Parke, H. L., Panagioti, M., Daines, L., Pearce, G., Epiphaniou, E., Bower, P., Sheikh, A., Griffiths, C. J., Taylor, S. J., & PRISMS and RECURSIVE groups (2017). Systematic meta-review of supported self-management for asthma: a healthcare perspective. BMC Medicine, 15, 64. https://doi.org/10.1186/s12916-017-0823-7.

Porsbjerg, C., & Menzies-Gow, A. (2017). Co-morbidities in severe asthma: Clinical impact and management. Respirology, 22, 651–661. https://doi.org/10.1111/resp.13026.

Powell, H., & Gibson, P. G. (2003). Options for self-management education for adults with asthma. The Cochrane Database of Systematic Reviews, CD004107. https://doi.org/10.1002/14651858.CD004107.

Pruneti, C. A. (2011). The P Stress Questionnaire: a new tool for the evaluation of stress-related behaviors. European Journal of Clinical Psychology and Psychiatry, 6, 1–37.

Pruneti, C., & Guidotti, S. (2022a). Cognition, behavior, sexuality, and autonomic responses of women with hypothalamic amenorrhea. Brain Sciences, 12, 1448. https://doi.org/10.3390/brainsci12111448.

Pruneti, C., & Guidotti, S. (2022b). Physiological stress as risk factor for hypersensitivity to contrast media: a narrative review of the literature and a proposal of psychophysiological tools for its detection. Physiologia, 2, 55–65. https://doi.org/10.3390/physiologia2030006.

Rothe, T., Spagnolo, P., Bridevaux, P. O., Clarenbach, C., Eich-Wanger, C., Meyer, F., Miedinger, D., Möller, A., Nicod, L. P., Nicolet-Chatelain, G., Sauty, A., SteurerStey, C., & Leuppi, J. D. (2018). Diagnosis and management of asthma – the Swiss guidelines. Respiration, 95, 364–380. https://doi.org/10.1159/000486797.

Rucci, P., De Marco, P., & Bivi, R. (1994). Il Symptom Questionnaire come strumento di screening nei contesti sanitari di base [The Symptom Questionnaire as a screening tool in primary healthcare settings]. Epidemiologia e Psichiatria Sociale, 3, 31–37. https://doi.org/10.1017/S1121189X00009295.

Sahiner, U. M., Birben, E., Erzurum, S., Sackesen, C., & Kalayci, Ö. (2018). Oxidative stress in asthma: Part of the puzzle. Pediatric Allergy and Immunology, 29, 789–800. https://doi.org/10.1111/pai.12965.

Shankar, M., Fagnano, M., Blaakman, S. W., Rhee, H., & Halterman, J. S. (2019). Depressive symptoms among urban adolescents with asthma: a focus for providers. Academic Pediatrics, 19, 608–614. https://doi.org/10.1016/j.acap.2018.12.004.

Uhlig, J., Lücke, C., Vliegenthart, R., Loewe, C., Grothoff, M., Schuster, A., Lurz, P., Jacquier, A., Francone, M., Zapf, A., Schülke, C., Thomas, D., May, M. S., Bremerich, J., Lotz, J., Gutberlet, M., & ESCR MRCT Registry contributors (2019). Acute adverse events in cardiac MR imaging with gadolinium-based contrast agents: Results from the European Society of Cardiovascular Radiology (ESCR) MRCT Registry in 72,839 patients. European Radiology, 29, 3686–3695. https://doi.org/10.1007/ s00330-019-06171-2.

Vazquez, K., Sandler, J., Interian, A., & Feldman, J. M. (2017). Emotionally triggered asthma and its relationship to panic disorder, ataques de nervios, and asthma-related death of a loved one in Latino adults. Journal of Psychosomatic Research, 93, 76–82. https://doi.org/10.1016/j.jpsychores.2016.11.010.

Wang, Y., Yao, L., Liu, L., Yang, X., Wu, H., Wang, J., & Wang, L. (2014). The mediating role of self-efficacy in the relationship between Big Five personality and depressive symptoms among Chinese unemployed population: a cross-sectional study. BMC Psychiatry, 14, 61. https://doi.org/10.1186/1471-244X-14-61.

Weiser, E. B. (2007). The prevalence of anxiety disorders among adults with asthma: a meta-analytic review. Journal of Clinical Psychology in Medical Settings, 14, 297–307. https://doi.org/10.1007/ s10880-007-9087-2.

World Health Organization (1995). The World Health Organization Quality of Life assessment (WHOQOL): Position paper from the World Health Organization. Social Science & Medicine, 41, 1403–1409. https://doi.org/10.1016/0277-9536(95)00112-k.

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Published

2023-12-15

How to Cite

Giordano, F., Guidotti , S., Giordano, T., & Pruneti, C. (2023). Clinical and psychological aspects in a group of allergic asthma patients and the impact on their health status perception. Health Psychology Report, 11(4), 321–330. Retrieved from https://czasopisma.bg.ug.edu.pl/index.php/HPR/article/view/10667

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