Academic Scientific JournalsProbiotics, prebiotics and intestinal microbiota transfer as therapeutic methods of autism spectrum disorders
Keywords:
intestinal microbiome, autism spectrum, fecal microbiota transfer, probiotics, prebioticsAbstract
In recent years, research on the correlation between the composition of the intestinal microbiome and the functioning of people with autism spectrum disorders has been increasingly observed in the scientific community. Autism Spectrum Disorder (ASD) is defined as a complex, heterogeneous neurodevelopmental disability disorder. Characterized by deficits in social interaction, communication, and stereotyped, repetitive behaviors, activities, and interests. The microbiome is a very diverse ecosystem that consists of 500 to 1000 different species of viruses, bacteria, fungi and protozoa. The species composition of microorganisms in the intestines varies from person to person, and is influenced by the current human health status, diet, age, metabolism, way of birth, geographical origin, stress, medications taken and the composition of the mother's microbiome. Intestinal microorganisms communicate with the central nervous system via the microbiota-gut- brain axis. It has been proven that people with ASD suffer from gastrointestinal disorders and colonic dysbiosis more often than neurotypical people. The scientific reports contained in the article indicate that probiotic therapy, the use of prebiotics and the transfer of intestinal microbiota are effective therapeutic methods for disorders occurring in people with autism spectrum disorders.
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